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In certain embodiments of a compound of Formula 1, at least one of R and R can be a chemotherapeutic moiety selected from N CH CH R, CH N CH CH R, N O CH CH R, CH N O CH CH R, N O CH CH R CH CH R, CH N O CH CH R CH CH R, O N CH CH R, CH O N CH CH R, CO N CH CH R, CH CO N CH CH R, O CO N CH CH R, and CH O CO N CH CH R, wherein each R is independently selected from Cl, Br, I, OSO CH, OSO CF, and hydroxyl OH; each of the other of R, R, R, R, and R can be hydrogen; R can be COOH; each R can be selected from hydrogen, methyl, hydroxyl, and fluoro; R can be selected from hydrogen, methyl, ethyl, propyl, isopropyl, cyclopropyl, tert butyl, methoxy, ethoxy, isopropoxy, trifluoromethyl, and trifluoromethoxy; and L can be selected from a bond, CH, C OH H, CHCH, C CH, CF, O, NR, CO, CH CH, CH CHCH, CHCH CH, CH CHOH, CHOH CH, CH CF, CF CH, CO NR, NR CO, CH NR, NR CH, CH O, O CH, CH S, S CH, CH SO, CH CO, and CO CH, wherein R is selected from hydrogen and methyl cialis on line MCF 7 cells were cultured with and without 10 10 M E 2 Sigma Aldrich Cat

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